The Acute Effect of and Energy Drink vs. Water Consumption on MAP, HR, and Energy Metabolism

Not Applicable

Completed

• Conditions: Cardiovascular Diseases; Hypertension; Diet
• Interventions: Dietary Supplement: Energy Drink; Other: Water Control

• Registration Number: NCT06330649
• Lead Sponsor: The University of Texas at Arlington

Brief Summary

The objective of this protocol is to investigate the effect of consumption of a commercially available energy drink beverage on blood pressure, heart rate, and energy metabolism

Detailed Description

Energy drink consumption has gained a lot in popularity and represents one of the most rapidly growing segments of the beverage industry. While regularly discussed in media outlets etc. the cardiovascular effects are not well described or well known. For example, the impacts on various cardiovascular parameters range from improved, decreased, to not impacted at all depending on the source. This can be due to a number of reasons including, study protocol design, study population tested, energy drink product used, volume consumed, etc. Accordingly, this study aims to investigate the impact of acute consumption of a standard commercially available can of energy drink beverage on the following parameters.

* Arterial blood pressure

* Heart rate

* Energy metabolism (oxygen consumption and carbon dioxide production

It is hypothesized that consumption of a 12 oz energy drink will result in modest elevations in arterial blood pressure, heart rate, and energy metabolism relative to when consuming of an equal volume of water.

Study Timeline

• Study Start: 2024-01-01
• Study First Submitted: 2024-03-12
• Study First Submitted QC: 2024-03-18
• Study First Posted: 2024-03-26
• Primary Completion: 2024-09-01
• Study Completion: 2024-09-01
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-26
• Last Update Posted: 2025-04-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Between ages 18-30
• Must be free of reported cardiovascular, respiratory, and metabolic diseases.
• Must be caffeine naïve
• Must be fasted

Exclusion Criteria

• Food allergies
• pregnant women
• Breast feeding women
• Individuals with cardiac, cardiovascular, respiratory, metabolic, and/or neurological disorders
• taking any prescription vasoactive medications
• allergies to spandex/lycra

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Energy Drink	Energy Drink	A commercially available caffeine drink containing 200 mgs of caffeine.
Water	Water Control	This will be 12 fl oz of commercially available water .

Primary Outcome Measures

Name	Time	Method
Oxygen consumption milliliters per kilogram of body weight per minute	baseline & 30, 60, 90, 120 min following beverage consumption	This will be assessed using a metabolic cart to measure the amount of oxygen that is consumed by the body.
Heart rate in beats per minute	baseline & 30, 60, 90, 120 min following beverage consumption	Heart will be measured using an electrocardiogram procedures that are done in a doctors office.
Peripheral blood pressure in millimeters of mercury	baseline & 30, 60, 90, 120 min following beverage consumption	blood pressure will be measured on the upper arm using standard procedures that are done in a doctors office.

Trial Locations

Locations (1)

UT Arlington - Science and Engineering Innovation and Research Building; 🇺🇸 Arlington, Texas, United States