The Individual Response of Healthy Individuals to Mental Fatigue: a Randomized Crossover Trial Investigating the Influence of Internal Factors in the Effects of Mental Fatigue on Human Performance
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 142
- 试验地点
- 2
- 主要终点
- Physical performance
研究概览
简要总结
The objective of the present study is to confirm and map out the presence of interindividual differences in the effect of mental fatigue on both physical and cognitive performance, and to see if these differences are related to individual factors of the participants.
详细描述
Every participant will visit the lab a total of three times within a period of two weeks. In the first visit, they will undergo both a detailed screening as well as perform all intervention/control trial measures to familiarize themselves with the utilised equipment. This detailed screening entails, among other things, a maximal incremental exercise test, a cognitive test battery and multiple subjective questionnaires.
The experimental and control trial are almost identical, with the only difference being the task performed in the middel of the trial. At the beginning of the trial the EEG will be fitted to the head of the participant and baseline measures will be taken. Afterwards, participants will perform a go nogo task to assess baseline cognitive performance. Then the intervention (i.e. Stroop task) or control (i.e. documentary) task will be performed. The goal of the Stroop task is to elicit mental fatigue, while the documentary provides a meaningful comparison. Afterwards, cognitive performance will again be assessed using the go no go task, followed by a physical performance task in the form of a time trial.
The different internal factors assessed during the screening stage will be correlated to the difference in cognitive and physical performance between the intervention and control trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
盲法说明
Participants are not informed as to what condition they are subjected.
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy (No neurological, cardiovascular or musculoskeletal disorders of any kind)
- •No prior knowledge of the concept of mental fatigue
- •No medication
- •Non-smoker
排除标准
- •Injuries of any kind in the past 6 months
- •Suffering from a chronic health condition (could be neurological, cardiovascular, internal and musculoskeletal)
- •Participating in any concomitant care or research trials
- •History of suffering from any mental/psychiatric disorders
- •Suffering from a higher risk of burn out, indicated by a total score of ≥ 2.59 on the Burn out assessment tool (BAT)
- •Suffering from high general fatigue, indicated by a score of >59 on the Multidimensional fatigue inventory (MFI)
- •Suffering from depression, indicated by a score of >16 on the Beck depression inventory-II (BDI-II)
- •Use of medication
- •Use of caffeine and heavy efforts 24 hours prior each trial
- •Suffering from colour vision deficiencies
- •Not eating a standardized meal, the morning of each trial
结局指标
主要结局
Physical performance
时间窗: through study completion, an average of 2 years
Participants will perform a time trial to assess physical performance. Participants will be able to start a 3 min fixed intensity warm-up. The trial itself lasts 15 min and participants are instructed to cover as much distance as possible. To keep the influence of motivation to a minimum, no encouragements or performance feedback will be given during the trial. The participants will only see the amount of time they have left on a digital chronometer. After the trial, a 2 min self-paced cooldown period will start. The evaluted outcome will be total workload performed by the participants (in kJ).
Cognitive performance: Go NoGo task: response inhibition
时间窗: through study completion, an average of 2 years
Cognitive performance will be assessed using a task based on the go/no-go paradigm. Participants are to react to different stimuli displayed on a computer screen positioned about 1 meter from the subject, preceded by a screen with general instructions. Two different stimuli were present at the same time: a Go or NoGo stimuli, and a left or right stimuli (meaning that four combinations are possible: GoRight, GoLeft, NoGoRight and NoGoLeft). If a Go stimuli is presented, participants are instructed to react to the left or right stimuli with the corresponding arrows. However, if a NoGo stimulus is presented, participants are instructed to refrain from reacting to the either the left or right stimuli. This proposed paradigm measures attention, response inhibition and working memory. Stimuli will be presented for 500 ms, with a varying interstimulus time between 1100 and 1700 ms. Outcome for response inhibition will be accuracy on the NoGo trials.
Cognitive performance: Go NoGo task: attention
时间窗: through study completion, an average of 2 years
Cognitive performance will be assessed using a task based on the go/no-go paradigm. Participants are to react to different stimuli displayed on a computer screen positioned about 1 meter from the subject, preceded by a screen with general instructions. Two different stimuli were present at the same time: a Go or NoGo stimuli, and a left or right stimuli (meaning that four combinations are possible: GoRight, GoLeft, NoGoRight and NoGoLeft). If a Go stimuli is presented, participants are instructed to react to the left or right stimuli with the corresponding arrows. However, if a NoGo stimulus is presented, participants are instructed to refrain from reacting to the either the left or right stimuli. This proposed paradigm measures attention, response inhibition and working memory. Stimuli will be presented for 500 ms, with a varying interstimulus time between 1100 and 1700 ms. Outcome for attention will be reaction time on the Go trials.
次要结局
- Age(through study completion, an average of 2 years)
- Subjective Manipulation check: M-VAS(through study completion, an average of 2 years)
- Behavioural Manipulation check: Stroop reaction time(through study completion, an average of 2 years)
- Behavioural Manipulation check: Stroop accuracy(through study completion, an average of 2 years)
- Physiological manipulation check - EEG (theta and alpha power and ERPs)(through study completion, an average of 2 years)
- Response inhibition(through study completion, an average of 2 years)
- Trait Self control(through study completion, an average of 2 years)
- Trait Anxiety(through study completion, an average of 2 years)
- Physical training level (subjective)(through study completion, an average of 2 years)
- Genetics(through study completion, an average of 2 years)
- Chronotype(through study completion, an average of 2 years)
- Length(through study completion, an average of 2 years)
- Fat percentage(through study completion, an average of 2 years)
- Sport participation(through study completion, an average of 2 years)
- Caffeine use(through study completion, an average of 2 years)
- Weight(through study completion, an average of 2 years)
- Sex(through study completion, an average of 2 years)
- Recovery need(through study completion, an average of 2 years)
- Physical training level (objective)(through study completion, an average of 2 years)
- Working memory(through study completion, an average of 2 years)
- Burn out(through study completion, an average of 2 years)
- Attention(through study completion, an average of 2 years)
- Sleep quality(through study completion, an average of 2 years)
- Mental Toughness(through study completion, an average of 2 years)
研究者
Bart Roelands
Professor
Vrije Universiteit Brussel