*The effect of duration of wound drainage on allogeneic blood transfusions using a postoperative retransfusion system after major orthopaedic surgery*

Completed

• Conditions: 10023213; 10003184; blood transfusion; osteoarthritits

• Registration Number: NL-OMON35562
• Lead Sponsor: Medisch Centrum Haaglanden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 570

Inclusion Criteria

- Patients scheduled to undergo elective major orthopaedic surgery (hip, knee)
- Male and non-pregnant female patients between 18-80 years of age.
- Patients who signed the Ethics Committee approved specific Informed Consent Form prior to surgery.

Exclusion Criteria

- Patients with a major surgical procedure during the 12 weeks before the study-related operation.
- No other used alternatives to reduce allogeneic blood transfusions, such as preoperative epoetin alpha (Eprex®) injections or intra-operative cell saving (Sangvia®).
- Clinical or laboratory evidence of untreated iron, folate or vitamin B12 deficiency.
- Recent Myocardial Infarction or CVA (<3 months).
- Dutch language not mastered.
- The patient is pregnant or planning a pregnancy after surgery (or is using inadequate birth control).
- Mentally disabled patients.
- Current malignancy or any active infection.

Study & Design

• Study Type: Interventional
• Study Design: Not specified