Database of Interstitial Lung Diseases

• Conditions: Interstitial Lung Diseases

• Registration Number: NCT00267800
• Lead Sponsor: St. Antonius Hospital

Brief Summary

The cause of most interstitial lung diseases (ILDs) is still unknown. Further research, for example to determine predisposing genetic factors, is therefore needed. A database with relevant clinical data and DNA/serum samples of ILD patients could facilitate future research on the cause of ILDs.

Detailed Description

Protocol title: 'Registration of clinical data and DNA of patients with Interstitial Lung Disease (ILD)' Rationale: The etiopathogenesis of most Interstitial Lung Diseases (ILDs) is still unknown. Further research, e.g. to determine predisposing genetic factors, is therefore needed. A database with relevant clinical data and DNA/serum samples of ILD patients could facilitate future research on the etiopathogenesis of ILDs.

Objective: Availability of relevant clinical data and DNA/serum samples of ILD patients in a database. Those data can be used for future research.

Study design: A prospective observational study

Study population: Patients diagnosed with ILD attending the pulmonology department in participating hospitals.

Intervention: a blood sample is taken from each patient. Furthermore, additional information is collected from the medical file.

Main study parameters/endpoints: DNA and serum sample, demographic variables, medical information, occupational history and hobbies.

Nature and extent of the burden and risks associated with participation, group relatedness: two tubes of blood will be drawn from the patients. The risks of drawing blood from a vein are minimal.

Study Timeline

• Status Verified: 2005-12
• Study First Submitted: 2005-12-19
• Study First Submitted QC: 2005-12-19
• Study First Posted: 2005-12-21
• Study Start: 2006-01
• Last Update Submitted: 2008-08-07
• Last Update Posted: 2008-08-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100000

Inclusion Criteria

• Diagnosis of an ILD, as stated by the American Thoracic Society (ATS)

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (4)

St. Antonius Hospital; 🇳🇱 Nieuwegein, Netherlands

Diakonessenhuis; 🇳🇱 Utrecht, Netherlands

UMC Utrecht; 🇳🇱 Utrecht, Netherlands

Mesos Medisch Centrum; 🇳🇱 Utrecht, Netherlands