Investigation of the effect of saffron on asthma
Not Applicable
Recruiting
- Conditions
- Moderate persistent allergic asthma.Moderate persistent allergic asthma
- Registration Number
- IRCT20180418039354N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 76
Inclusion Criteria
Age between 18 to 65 years old
Moderate persistent allergic asthma according to the physician
Normal body mass index (up to 27)
Exclusion Criteria
Smoking
Diabetes
Pregnancy and lactation
Autoimmune disease, malignancies, gastrointestinal, liver and kidney disease, pneumonia and other pulmonary disease
Taking antioxidant supplements
Unwilling to continue the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Interleukin 10 (IL-10). Timepoint: The beginning and end of supplementation. Method of measurement: ELISA method.;Transforming growth factor ß (TGF-ß). Timepoint: The beginning and end of supplementation. Method of measurement: ELISA method.;Interleukin 35 (IL-35). Timepoint: The beginning and end of supplementation. Method of measurement: ELISA method.;Prooxidant-antioxidant Balance (PAB). Timepoint: The beginning and end of supplementation. Method of measurement: ELISA method.
- Secondary Outcome Measures
Name Time Method Complete Blood Count-differential (CBC-diff). Timepoint: The beginning and end of the supplementation. Method of measurement: Will be assessed by Sysmex device.;A frequency of shortness of breath in the day or night. Timepoint: The beginning and end of the supplementation. Method of measurement: Based on the patient's response (number per week).;How often do you wake up because of asthma symptoms. Timepoint: The beginning and end of the supplementation. Method of measurement: Based on the patient's response (number per week).;Frequency of activity limitation due to asthma and shortness of breath. Timepoint: The beginning and end of the supplementation. Method of measurement: Based on the patient's response (number per week).;The frequency of use of salbutamol spray. Timepoint: The beginning and end of the supplementation. Method of measurement: Based on the patient's response (number per week).