The safety and efficacy of Laparoscopic Gastric Plication versus Laparoscopic sleeve gastrectomy in the treatment of morbid obesity
Phase 2
- Conditions
- Morbid obesity.Morbid obesity
- Registration Number
- IRCT2013123012294N5
- Lead Sponsor
- Vice chancellor for research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
morbid obesity ( BMI>40 kg/m2 or BMI>35kg/m2 with co-existing morbidities ); age 18 to 65; previous unsuccessful weight loss attempts Exclusion criteria: previous restrictive or malabsorptive procedure for obesity treatment; previous gastric surgery; history of anti-reflux surgery; pregnancy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percent of excess weight loss. Timepoint: 24 months after surgery. Method of measurement: Weighing.;Operative time. Timepoint: During surgery. Method of measurement: With a clock.;Length of hospitalization. Timepoint: after discharging. Method of measurement: days of hospitalization.;Hypertension. Timepoint: 24 months follow-up. Method of measurement: clinical examination and non invasive blood pressure measurement.;Diabetes. Timepoint: 24-months follow-up. Method of measurement: FBS , HgA1c.;Hyperlipidemia. Timepoint: 24 months follow-up. Method of measurement: cholesterol level,triglyceride.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms differentiate Laparoscopic Gastric Plication from Sleeve Gastrectomy in weight regulation?
How does Laparoscopic Gastric Plication compare to standard-of-care bariatric procedures in long-term metabolic outcomes?
Are there specific biomarkers that predict better outcomes with Laparoscopic Sleeve Gastrectomy versus Gastric Plication?
What are the potential adverse events associated with Laparoscopic Gastric Plication and how do they compare to Sleeve Gastrectomy?
What combination approaches or alternative bariatric procedures are being explored alongside Laparoscopic Gastric Plication for morbid obesity treatment?