Changes in the oral environment according to the application of mouthwash containing Cibotium barometz J. Smith

Not Applicable

Completed

• Conditions: Not Applicable

• Registration Number: KCT0008497
• Lead Sponsor: Kangwon National University

Brief Summary

Application of mouthwash containing Cibotium barometz J. Smith extract significantly decreased clinical values in all indicators of oral microbes, O’Leary index, PI, and GI (p<0.05). In addition, after gargling with a mouthwash containing Cibotium barometz J. Smith extract, the antibacterial action on Gram-negative and Gram-positive bacteria that cause oral disease showed an excellent clinical effect in inhibiting, preventing, and treating oral diseases. The use of the mouthwash containing Cibotium barometz J. Smith extract was found to be effective for oral desease related indicators and bacteria causing oral disease. In addition, it was confirmed that the oral environment was improved as a result of saliva analysis and halitosis measurement. Therefore, using a mouthwash containing Cibotium barometz J. Smith extract, a natural drug, will possibly maintain healthy oral health by inhibiting and preventing the progression of oral disease.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2023-04-30
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

Participants in this study were healthy individuals without systemic disease among patients who agreed to fill out the questionnaire.

Exclusion Criteria

Among the study participants, those with severe dental diseases (such as periodontitis, dental caries, dry mouth, etc.) (except for one or more dental caries), those who are currently treated for liver disease, kidney disease, Schogren's syndrome, and antibiotics within 2 months) were excluded..

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mmicrobiological analysis

Secondary Outcome Measures

Name	Time	Method
O’Leary index ;Plaque index (PI);Evaluation of improvement by test subjects themselves;Gingival index (GI) ;Cariview;Salivary test;Bad breath measurement by BB checker