Pulmonary Vein Isolation with Irreversible Electroporation, a pilot study - PVI using IRE

niversitair Medisch Centrum Utrecht0 个研究点目标入组 10 人开始时间: 待定最近更新: 2024年2月28日

适应症

试验速览

暂无简介。

•- Patients age is * 18 years and * 80 years
•- Patients must provide written, informed consent
•- Patients with paroxysmal or persistent drug-refractory, symptomatic atrial fibrillation. Persistent AF is defined as sustained episodes of atrial fibrillation lasting >7 days.
•- Patients undergoing a first time ablation procedure for atrial fibrillation
•- All pulmonary vein diameters at computed tomography or magnetic resonance imaging * 23 mm
•- AF must be recorded at least once by ECG, holter, telemetry, loop recorder or internal device
•- Patients have non-valvular AF

•- Not capable of giving informed consent
•- Prior PVAI with RF or Cryo ablation
•- Patients with longstanding persistent AF (defined as sustained episode lasting >1 year)
•- One or more PVs with a diameter at computed tomography or magnetic resonance imaging > 23 mm
•- Patients with any exclusion criteria or contra-indications for electrophysiologic study and ablation in the LA, such as pregnancy or presence of a LA thrombus

发起方

niversitair Medisch Centrum Utrecht