Exercise as an Adjuvant Therapy for Veterans With PTSD
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 54
- 试验地点
- 1
- 主要终点
- Physical Activity
研究概览
简要总结
The purpose of this study is to examine whether posttraumatic stress disorder (PTSD) symptoms impact adherence to a 12-week physical activity program and whether exercise can help improve PTSD symptoms and health outcomes in older Veterans. Veterans over the age of 60 with PTSD were be recruited to participate in a 12-week physical activity program consisting of aerobic and strengthening activities. 54 participants were randomized to an intervention arm (n=36) or usual care wait-list control (n=18).
详细描述
There is substantial evidence that physical inactivity contributes to poorer physical health outcomes in older adults. There is a paucity of work examining physical activity in Veterans with PTSD. Consequently, the efficacy of exercise as a beneficial adjunctive therapy in the treatment for PTSD symptoms and related health sequelae has not been established. Methods: Approximately 50 Veterans 60 years and older with PTSD will be recruited to participate in a 12-week physical activity program consisting of aerobic and strength-training activities. Participants will be randomized to an intervention arm or usual care wait-list control. Outcomes: Changes in physical function, PTSD symptom severity, and aerobic endurance will be assessed between the two study arms. Summary: This pilot trial will extend the investigators' understanding of the physical and psychological benefits of physical activity in Veterans with PTSD. The results from this study will be used to be used to develop a larger, randomized controlled exercise trial for Veterans with PTSD. Once new, effective exercise therapies for Veterans with PTSD are established, we can augment traditional PTSD therapy with exercise therapy to promote the prevention and treatment of chronic diseases common in this vulnerable population.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meet diagnostic criteria for current PTSD,
- •live within 50 miles of Durham VA Medical Center (VAMC) and have reliable transportation,
- •registered for care at the Durham VAMC,
- •independently mobile (assistive devices acceptable),
- •speak and write fluent conversational English
排除标准
- •Active substance dependence other than nicotine,
- •cognitive impairment, uncontrolled psychotic symptoms,
- •clinical history of cardiovascular disease (CVD) occurring within the past 3 months,
- •uncontrolled hypertension,
- •renal disease or currently receiving dialysis,
- •psychotropic medication initiated within 6 weeks prior to enrollment
- •proliferative retinopathy
研究组 & 干预措施
Physical Activity
Participants randomized to this arm will be enrolled in a 12-week physical activity program.
干预措施: Exercise as an Adjuvant Therapy for Veterans with PTSD (Behavioral)
Usual Care Wait-List
Participants randomized to this arm will continue to receive usual care services for PTSD through the Veterans Health Administration (VHA) for 12 weeks after which time they will be offered the physical activity program for 12 weeks.
结局指标
主要结局
Physical Activity
时间窗: Baseline and 12 Weeks
Activity levels (metabolic equivalent \[MET\]-minutes/week) were measured using the Aerobic Center Longitudinal Study physical activity questionnaire.
Feasibility of Patient Recruitment
时间窗: Baseline
The primary aim/outcome of this pilot study is the feasibility of recruiting older Veterans with PTSD to participate in a 12-week exercise program. The number of Veterans recruited out of the total number contacted will be determined at baseline.
PTSD Symptoms
时间窗: Baseline and 12 Weeks
PTSD symptom severity was assessed at both baseline and 12 Weeks using the PTSD Checklist for DSM-V (PCL-5). Scores on the PCL-5 range from 0 to 80, with higher scores indicating more severe PTSD symptoms.
次要结局
- Aerobic Endurance(Baseline and 12 Weeks)