Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan
Overview
- Phase
- Not Applicable
- Intervention
- Propofol
- Conditions
- Emergence Agitation
- Sponsor
- Khon Kaen University
- Enrollment
- 134
- Locations
- 1
- Primary Endpoint
- incidence of emergence agitation
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this clinical trial is to compare Efficacy of low dose propofol(0.5 mg/kg) vs placebo given at the end of sevoflurane anesthesia for prevention of emergence agitation in pediatric patient undergoing MRI scan. The main question it aims to answer is "Can low dose propofol reduce the incidence of emergence agitation after general anesthesia?" Participants will be given propofol 0.5 mg/kg or saline according to the allocated group at the completion of MRI scan
Investigators
Santhita Pimonbut
Santhita Pimonbut
Khon Kaen University
Eligibility Criteria
Inclusion Criteria
- •Age 2-8 years
- •ASA class I or II ,who schedule for MRI scan under sevoflurane anesthesia
Exclusion Criteria
- •Developmental delay
- •Psychological and neurological disorders
- •Abnormal airway
- •Reactive airway disease
- •Allergy to propofol, egg product
- •Family history of malignant hyperthermia
- •Need iv sedative medication before induction
Arms & Interventions
group P
Receive 0.5 mg/kg of propofol intravenously at end of sevoflurane anesthesia
Intervention: Propofol
group S
Receive saline intravenously at end of sevoflurane anesthesia
Intervention: Normal saline
Outcomes
Primary Outcomes
incidence of emergence agitation
Time Frame: at 5,10,15,20,25,30 minutes after extubation
Secondary Outcomes
- Incidence of complication(2 hours after extubation)
- Use of rescue medication(2 hours after extubation)
- Length of stay in post anesthetic care unit(2 hours after extubation)
- Emergence time(2 hours after extubation)