Transjugular Intrahepatic Portosystemic Shunts Improve Survival in Patients With Cirrhosis and Recurrent Ascites
- Conditions
- Refractory Ascites
- Interventions
- Procedure: transjugular intrahepatic portal shunt
- Registration Number
- NCT06196723
- Lead Sponsor
- Tang-Du Hospital
- Brief Summary
Currently, there is limited evidence regarding the survival benefit of early transjugular intrahepatic portal shunt (TIPS) placement in patients with cirrhosis and recurrent ascites. This observational study aimed to assess whether early TIPS improves the survival of patients with advanced cirrhosis and recurrent ascites. We will compare large volume paracenteses plus albumin (LVP+A） to see if TIPS improves the survival of patients with advanced cirrhosis and recurrent ascites.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 462
Definite diagnosis of recurrent ascites in cirrhosis (based on clinical symptoms, laboratory and imaging studies, or liver biopsy) TIPS or LVP+A therapy, -
Malignant neoplasm, including hepatocellular carcinoma with extrahepatic metastasis Prior liver transplantation Severe heart and lung dysfunction Recurrent hepatic encephalopathy Concomitant active infection TIPS with the use of uncovered stents Complete portal vein thrombosis
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description TIPS transjugular intrahepatic portal shunt transjugular intrahepatic portal shunt
- Primary Outcome Measures
Name Time Method One year transplant free survival One year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (3)
Tangdu hospital
🇨🇳Xian, Shaanxi, China
Xi'an International Medical Center Hospital
🇨🇳Xian, Shaanxi, China
Xijing hospital
🇨🇳Xian, Shaanxi, China