A Comparison of Epidural Block With Adding Sciatic Block to Continuous Femoral Block in Total Knee Arthroplasty

Not Applicable

• Conditions: Postoperative Pain
• Interventions: Device: epidural infusion; Device: femoral sciatic

• Registration Number: NCT02235506
• Lead Sponsor: Yeungnam University College of Medicine

Brief Summary

The investigators compared continuous epidural infusion with combined continuous femoral and single-shot sciatic nerve blocks. The primary outcome was the incidence of side effects, and secondary outcomes were pain relief, motor blockade,morphine consumption, and rehabilitation indices.

Detailed Description

The parcicipants were randomly assingned to epidural infusion group and femoral sciatic block. In epidural infusion group, a lumbar epidural catheter was placed at the L3-4 level using loss-ofresistance procedure. ropivacaine 0.2% and fentayl 2mcg/ml were infused at a rate of 5ml/hr from the end of operation. In femoral sciatic group, the femoral and sciatic nerve are located using ultrasound and 0.2% ropivacain is injected. A catheter is inserted to femoral nerve. From the end of operation, 0.2% ropivacaine was infused through the femoral catheter at a rate of 5ml/hr. The incidence of side effects is measured.

Study Timeline

• Study Start: 2014-09
• Study First Submitted: 2014-09-01
• Study First Submitted QC: 2014-09-05
• Study First Posted: 2014-09-10
• Status Verified: 2015-07
• Last Update Submitted: 2015-07-14
• Last Update Posted: 2015-07-16
• Primary Completion: 2016-06
• Study Completion: 2016-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• American Society of Anesthesiologists Physical Status Classification I-II
• total knee arthroplasty
• 18-90 years

Exclusion Criteria

• allergic to the local anesthetics
• cognitive impairment such as dementia
• coagulopathy
• motor and sensory impairment
• patient refusal
• BMI >39

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
epidural infusion	epidural infusion	In epidural infusion group, a lumbar epidural catheter was placed at the L3-4 level using loss-ofresistance procedure. ropivacaine 0.2% and fentayl 2mcg/ml were infused at a rate of 5ml/hr from the end of operation,
femoral sciatic	femoral sciatic	In femoral sciatic group, the femoral and sciatic nerve are located using ultrasound and 0.2% ropivacain is injected. A catheter is inserted to femoral nerve. From the end of operation, 0.2% ropivacaine was infused through the femoral catheter at a rate of 5ml/hr.

Primary Outcome Measures

Name	Time	Method
the incidence of side effects	during 5 days after the end of operation	Side effects: The patients were asked to their experience of dizziness, sedation, nausea/vomiting (PONV), and pruritus. Urinary retention: bladder volume was measured by ultrasonography and if the volume was more than 400 mL and if the patient was unable to void spontaneously, single catheterization was performed.

Secondary Outcome Measures

Name	Time	Method
Pain	during 5 days after the end of operation	Pain according to visual analogue scale at rest and on mobilization.
Motor blockade at rest and on mobilization	during 5 days after the end of operation	Motor blockade is estimated using a modified Bromage scale

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Yeungnam University hospital; 🇰🇷 Daegu, Korea, Republic of