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Clinical Trials/NCT02235506
NCT02235506
Unknown
N/A

A Comparison of Epidural Analgesia With Adding Sciatic Nerve Block to Continuous Femoral Nerve Block for Post-operative Pain Management Following Total Knee Arthroplasty

Yeungnam University College of Medicine1 site in 1 country80 target enrollmentSeptember 2014

Overview

Phase
N/A
Intervention
Not specified
Conditions
Postoperative Pain
Sponsor
Yeungnam University College of Medicine
Enrollment
80
Locations
1
Primary Endpoint
the incidence of side effects
Last Updated
10 years ago

Overview

Brief Summary

The investigators compared continuous epidural infusion with combined continuous femoral and single-shot sciatic nerve blocks. The primary outcome was the incidence of side effects, and secondary outcomes were pain relief, motor blockade,morphine consumption, and rehabilitation indices.

Detailed Description

The parcicipants were randomly assingned to epidural infusion group and femoral sciatic block. In epidural infusion group, a lumbar epidural catheter was placed at the L3-4 level using loss-ofresistance procedure. ropivacaine 0.2% and fentayl 2mcg/ml were infused at a rate of 5ml/hr from the end of operation. In femoral sciatic group, the femoral and sciatic nerve are located using ultrasound and 0.2% ropivacain is injected. A catheter is inserted to femoral nerve. From the end of operation, 0.2% ropivacaine was infused through the femoral catheter at a rate of 5ml/hr. The incidence of side effects is measured.

Registry
clinicaltrials.gov
Start Date
September 2014
End Date
June 2016
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Sangjin Park

assistant professor

Yeungnam University College of Medicine

Eligibility Criteria

Inclusion Criteria

  • American Society of Anesthesiologists Physical Status Classification I-II
  • total knee arthroplasty
  • 18-90 years

Exclusion Criteria

  • allergic to the local anesthetics
  • cognitive impairment such as dementia
  • coagulopathy
  • motor and sensory impairment
  • patient refusal

Outcomes

Primary Outcomes

the incidence of side effects

Time Frame: during 5 days after the end of operation

Side effects: The patients were asked to their experience of dizziness, sedation, nausea/vomiting (PONV), and pruritus. Urinary retention: bladder volume was measured by ultrasonography and if the volume was more than 400 mL and if the patient was unable to void spontaneously, single catheterization was performed.

Secondary Outcomes

  • Pain(during 5 days after the end of operation)
  • Motor blockade at rest and on mobilization(during 5 days after the end of operation)

Study Sites (1)

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