Assessment of Oral Caffeine Intake in Reducing the Severity of Acute Migraine Attack Among Patients Attending Headache and Neurology Outpatients Clinic of Ainshams University Hospitals: A Randomized Controlled Trial
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- To reduce the severity of migraine attack
研究概览
简要总结
Caffeine extracted from green tea to abort acute attack of Migraine
详细描述
Caffeine tablets extracted from green tea can be used as caffeinated drinks to decrease intensity of migraine attacks
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients suffering from migraine with aura, migraine without aura, episodic, and chronic migraine according to ICHD-3 diagnosis will be legible for the study.
排除标准
- •Patients who have history of any cardiac dysrhythmia, hypertension, ischemic heart disease, active peptic ulcer disease, inflammatory bowel disease, obsessive compulsive disorder, pregnancy, breast-feeding, renal failure, hepatic failure, sleep disorder, mental retardation, and history of substance abuse that prevent them from cooperating with us during the study Patients who had headache due to: Cluster headache, trigeminal neuralgia, glossopharyngeal neuralgia, headache secondary to trauma, cranial disorder, vascular disorder, infection, or mass lesion, will also be excluded
研究组 & 干预措施
Caffeine group
Caffeine group added to standard treatment
干预措施: Caffeine (200 mg) (Drug)
Caffeine group
Caffeine group added to standard treatment
干预措施: triptans (Drug)
Caffeine group
Caffeine group added to standard treatment
干预措施: NSAID (Nonsteroidal anti-inflammatory drugs) (Drug)
Caffeine group
Caffeine group added to standard treatment
干预措施: Paracetamol (acetaminophen) (Drug)
Control group
Standard treatment (NSAIDS, Triptans, or Acetaminophen)
干预措施: triptans (Drug)
Control group
Standard treatment (NSAIDS, Triptans, or Acetaminophen)
干预措施: NSAID (Nonsteroidal anti-inflammatory drugs) (Drug)
Control group
Standard treatment (NSAIDS, Triptans, or Acetaminophen)
干预措施: Paracetamol (acetaminophen) (Drug)
结局指标
主要结局
To reduce the severity of migraine attack
时间窗: Three years
using Visual analogue scale
次要结局
- To evaluate the effect of oral caffeine in reducing pain associated with acute migraine attacks among patients attending Headache Clinic, Ain Shams University hospital via Visual analogue scale(Three year)
研究者
Nourhan Nader
Assistant lecturer
Ain Shams University