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Transarterial, interventional radiological Treatment of hemorrhoidal disease

Not Applicable
Recruiting
Conditions
K64
Haemorrhoids and perianal venous thrombosis
Registration Number
DRKS00016683
Lead Sponsor
Klinikum der Universität München, Campus Großhadern
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

Patients with symptomatic internal hemorrhoids 2nd / 3rd degree, lack of response to prior therapies (conservative basic treatment, medication, endoscopic procedures, minimally invasive procedures, contraindication to surgery and failed surgical/endoscopic treatment, negative colonoscopic correlation (during the past 24 months), no existing promising alternative endovascular/surgical therapeutic option, platelet count = 50.000 / µl, PTT < 50 s, INR < 1,5, age-adjusted normal serum creatinine or creatinine clearance = 30 ml/min / 1,73 m² for safe application of contrast media.

Exclusion Criteria

feasible surgical or endoscopic treatment, hemorrhoidal disease 1st and 4th degree, fixed prolaps, absent access via superior mesenteric artery (e.g. after hemicolectomy), after rectal resection, after endovascular aortic repair (EVAR), acute diseases like fissures, infections, abscesses etc., anatomic contraindications: stenoses, fistula, vascular occlusions, prior colorectal surgery, colorectal anomalies, allergic reactions to contrast media, severe kidney failure, pregnancy.

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Evaluation of the therapeutic efficacy of the embolization of hemorroidal arteries by applying the French Bleeding Score and VAS 6 months post-interventionally.
Secondary Outcome Measures
NameTimeMethod
Improvement of quality of life.<br>Pain scale for determining the severity of the symptoms caused by the hemorrhoids
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