The effect of zolpidem and amantadine on the level of consciousness in patients diffuse axonal injury
Phase 3
- Conditions
- diffuse axonal injury.????????? ?? ??? ????? ????? ?? ????? ???? ?????G35-G37
- Registration Number
- IRCT20191026045243N1
- Lead Sponsor
- Sari University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 66
Inclusion Criteria
1. Confirmation of axonal injury published by a specialist in neurosurgery
2. GCS less than or equal to 8
3. Age between 15 and 70 years
4. Hospitalized less than 8 hours after injury
5. Informed consent from the patient's companions for inclusion in the study
Exclusion Criteria
1. Patient's or guardian's dissatisfaction with the study
2. A history of drug allergy to zolpidem or amantadine
3. History of any previous brain trauma
4. History of any previous brain procedure
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Increased awareness and speed of recovery for patients with cognitive problems and brain injuries. Timepoint: During these 8 days and up to 3 days after discontinuation of the drug. Method of measurement: Glasgow Coma Scale.
- Secondary Outcome Measures
Name Time Method