Phacoemulsification Combined With Posterior Capsulotomy in Cataract Complicated With Primary Posterior Capsule Opacification: a Randomized Controlled Trial
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cataract
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- LogMAR visual acuity 1 month postoperatively
- Last Updated
- 7 years ago
Overview
Brief Summary
This is a two-arm, parallel group, open-label, randomized controlled trial to compare the visual acuity, visual quality, operative complications and the satisfaction of patients between primary posterior capsulorhexis group and laser capsulotomy group of cataract patients combined with primary posterior capsular opacification (PPCO).
Detailed Description
Primary posterior capsular opacification (PPCO) refers to the posterior capsule opacification which cannot be removed by polishing or vacuuming during cataract surgery. The surgeon may have to decide on primary posterior capsulorhexis or early neodymium-doped yttrium aluminum garnet (Nd:YAG) laser capsulotomy in these cases. The aim of this study is to compare the visual acuity, visual quality, operative complications and the satisfaction of patients between primary posterior capsulorhexis group and laser capsulotomy group of cataract patients combined with primary posterior capsular opacification (PPCO).
Investigators
Yizhi Liu
Clinical Professor,director of Zhongshan Ophthalmic Center
Zhongshan Ophthalmic Center, Sun Yat-sen University
Eligibility Criteria
Inclusion Criteria
- •Cataract patients with primary posterior capsular opacification, which involves the central posterior capsular and interferes with visual axis;
- •Aged 18 years or over;
- •With best corrected visual acuity (BCVA) less than 0.3.
Exclusion Criteria
- •History of other eye disease that contributes to visual impairment, including keratopathy, uveitis, glaucoma, retinopathy, ocular trauma, or intraocular surgery.
- •Cases with operative complications, including anterior or posterior capsular rupture, lens suspensory ligament rupture, the falling of lens nucleus into vitreous cavity.
- •Unwillingness to participate in the study.
Outcomes
Primary Outcomes
LogMAR visual acuity 1 month postoperatively
Time Frame: 1 month
Best corrected visual acuity (LogMAR) will be measured 1 month postoperatively.
Secondary Outcomes
- Modulation transfer function cut off (MTF cut off)(3 months)
- Rate of intraocular lens damage(3 months)
- Object scatter index (OSI)(3 months)
- Predicted visual acuity (PVA) with contrasts of 100%, 20% and 10%(3 months)
- Rate of retinal detachment(3 months)
- Rate of ocular hypertension(3 months)
- Rate of ocular macular edema(3 months)
- Dysfunctional lens index (DLI)(3 months)
- Internal higher order aberration (HOAs)(3 months)
- Strehl ratio (SR)(3 months)
- Visual-functioning index 7 score(3 months)