Comparative study between intravenous Dexmedetomidine and intravenous fentanyl for smooth extubation and Emergence after general anaesthesia
Overview
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- To determine the effect of intravenous Dexmedetomidine vs intravenous fentanyl for smooth extubation and Emergence after general anaesthesia
Overview
Brief Summary
This prospective randomized comparative study will evaluate intravenous dexmedetomidine versus intravenous fentanyl for smooth extubation and emergence after general anesthesia. This study aims to compare the quality of extubation and hemodynamic responses during emergence. Secondary outcomes include emergence time, sedation score, postoperative pain, and adverse effects. The objective is to determine the safer and more effective drug for achieving smooth extubation and stable recovery.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients posted for elective surgery under general anaesthesia with duration upto 3hrs
- •Patients with ASA class I and class II.
Exclusion Criteria
- •Smoking history
- •History of drug allergy with either of the study drugs
- •More than two intubation attempts
- •Preoperative sore throat
- •Surgery involving airway
- •Difficult airway
- •Pregnant and lactating females.
Outcomes
Primary Outcomes
To determine the effect of intravenous Dexmedetomidine vs intravenous fentanyl for smooth extubation and Emergence after general anaesthesia
Time Frame: Peri operative monitoring of vitals that is pre induction , post induction, intra operative and post operative post extubation
Secondary Outcomes
- To compare postoperative pain in both groups.(Post extubation followed by 1hr, 2hr, 4hrs, 6hrs & 12hrs)
- To compare post operative adverse events such as nausea, vomiting, laryngospasm & bronchospasm in both the groups.(Post operative every 2 hours upto 12 hours)
Investigators
Aadhya bajaj
Mahatma Gandhi Medical College and Hospital