Effect of midazolam through nasal versus intravenous route in controlling seizures in children.
Phase 2
- Conditions
- Health Condition 1: G969- Disorder of central nervous system, unspecified
- Registration Number
- CTRI/2024/01/061644
- Lead Sponsor
- Government medical college and hospital, Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All children between the ages of 1 month and 18 years presenting with acute seizures for at least 5 minutes duration in pediatric emergency and in patient department of GMCH 32, Chandigarh
Exclusion Criteria
1) Non consenting parents
2) Children <5kg weight
3) Children with upper respiratory tract infections
4) Children who had received anticonvulsants within 1 hour before admission
5) Children with severe cardiorespiratory decompensation
6) Children with CSF rhinorrhea
7) Known allergy to benzodiazepines.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Seizure cessationTimepoint: Interval between arrival of patients at the hospital with active seizures/ witnessed seizures more than 5 minutes and the control of seizures
- Secondary Outcome Measures
Name Time Method Incidence of adverse drug reactions among the patients receiving intranasal & intravenous midazolam.Timepoint: 30 minutes