Effect of vitamin D supplementation on the pregnancy outcomes

Phase 2

Conditions: Condition 1: Pre-eclampsia. Condition 2: Vitamin D status in pregnant women and cord blood. Condition 3: Getational Diabetes Mellitus. Condition 4: Preterm delivery. Condition 5: Abortion.
Pre-eclampsia, unspecified
E55: Vitamin D deficiency
Diabetes mellitus arising in pregnancy (Gestational diabetes mellitus NOS)
Preterm labour and delivery
Spontaneous abortion

Registration Number: IRCT2016090329675N1

Lead Sponsor: Vice chancellor for research, Shahid Beheshti University of Medical Sciences, School of Nutrition an

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 126

Inclusion Criteria

Pregnant women aged at 18-40 years and their newborns, Singleton pregnancy. Exclusion criteria: Multiple pregnancy, Diagnosis any kind of diseases including renal, hepatic, and other disorders which could influence vitamin D metabolism during the study, Chronic hypertension, Receiving vitamin D or calcium supplements within the last three months, On any medication which could potentially influence vitamin D metabolism (notably estrogens, and calcitonin) within the last three months, Newborns with congenital anomalies.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vitamin D concentration of pregnant women serum. Timepoint: Baseline and after the intervention. Method of measurement: High performance liquid chromatography (HPLC).;Vitamin D concentration of Cord blood. Timepoint: At birth. Method of measurement: High performance liquid chromatography (HPLC).

Secondary Outcome Measures

Name	Time	Method
Growth indices of newborns. Timepoint: After Birth. Method of measurement: Infant's Records.;Preterm delivery. Timepoint: At less than 37 weeks of gestational age. Method of measurement: Pregnant women Records.;Abortion. Timepoint: During the first 28 weeks of pregnancy. Method of measurement: Pregnant women Records.;Gestational diabetes. Timepoint: At the gestational age of 24-28 weeks. Method of measurement: Pregnant women Records.;Preeclampsia. Timepoint: At the gestational age of 24-28 weeks. Method of measurement: Pregnant women Records.