Gastrointestinal effects of early enteral colostrum in very preterm infants - a retrospective analysis

Recruiting

• Conditions: Other intestinal obstruction of newborn; Other perinatal digestive system disorders; P78; Necrotizing enterocolitis of fetus and newborn; P76; P77

• Registration Number: DRKS00032611
• Lead Sponsor: niversitätskinderklinik Tübingen, Abteilung Neonatologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-09-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

Extremely preterm infants (<28 weeks gestational age) or small for gestational age (birthweight percentile<P10) very preterm infants (<32weeks gestational age)

Exclusion Criteria

Contraindications for enteral nutrition (i.e. gastrointestinal malformation, errors of metabolism), antenatal decision for palliative care, death within the first 5 days postnatally, outborn patients

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Combined adverse outcome (mortality/Surgery for NEC or FIP)

Secondary Outcome Measures

Name	Time	Method
All outcomes included in the primary Outcome, Start of Colostrum, Timing of Meconiumextretion, nutrition in the first 5 days postnatally, timing of succesfull enteral nutrition