Effect of Dietary Polyphenols on Insulin Sensitivity
Phase 1
Completed
- Conditions
- Insulin Resistance
- Registration Number
- NCT00668928
- Lead Sponsor
- United States Department of Agriculture (USDA)
- Brief Summary
A large and growing segment of the population is prediabetic. Dietary interventions that improve insulin sensitivity may be important in preventing the progression to full-blown diabetes in these individuals. Foods and dietary compounds that increase insulin sensitivity are likely to help maintain a healthier body composition. This pilot study will provide data to evaluate the role of dietary plant polyphenols in improving insulin sensitivity.
- Detailed Description
How does the amount consumed of cocoa and tea polyphenols (flavon-3-ol monomers and oligomers) affect insulin sensitivity in insulin resistant individuals?
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Individuals who are insulin resistant based on routine clinical measurements (Stern et al., 2005).
Exclusion Criteria
- BMI < 27 kg/m²
- Age < 25 and > 65 years
- Pregnant women or women who plan on becoming pregnant during the study
- Postpartum women
- Lactating women
- Diabetes mellitus
- Kidney disease
- Liver disease
- Certain cancers
- Smokers
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method