NCT01378052Unknown不适用
Level of DNA Methylation in People With Urothelial Carcinoma
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- urothelial carcinoma
研究概览
简要总结
Many studies previously showed the significant association between urinary arsenic profiles and urothelial carcinoma (UC) risk and observed the increased UC risk in people with lower plasma folate and higher homocysteine than those with higher plasma folate and lower homocysteine. The investigators would expect to explore the interactions among global DNA methylation, one-carbon metabolic pathway factors, urinary arsenic profiles and UC.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosis of urothelial carcinoma
- •The voluntary of participating the study
排除标准
- •Age smaller than 20 years
- •Pregnant women
- •Not willing to participate the study because of their personal reasons
结局指标
主要结局
urothelial carcinoma
时间窗: one year
Pathological verification of UC was done by routine urological practice including endoscopic biopsy or surgical resection of urinary tract tumors followed by histopathological examination by board-certified pathologists.
次要结局
未报告次要终点
研究者
研究点 (1)
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