Study on the Effect of Surgical Intestinal Manipulation

Not Applicable

• Conditions: Intestinal Manipulation
• Interventions: Other: blood sampling

• Registration Number: NCT02189512
• Lead Sponsor: Universitaire Ziekenhuizen KU Leuven

Brief Summary

The aim of this study is to study the impact of brain death and surgical small bowel manipulation on the release of different types of monocytes.

Detailed Description

Not available

Study Timeline

• Status Verified: 2014-05
• Study Start: 2014-05
• Study First Submitted: 2014-05-27
• Study First Submitted QC: 2014-07-10
• Last Update Submitted: 2014-07-10
• Study First Posted: 2014-07-14
• Last Update Posted: 2014-07-14
• Primary Completion: 2016-01
• Study Completion: 2016-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• patients who are brain death
• patients who undergo an elective abdominal aortic aneurysm repair

Exclusion Criteria

• < 18 years of age

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
brain death organ donors	blood sampling	cases - blood sampling
abdominal aortic aneurysm repair	blood sampling	controls - blood sampling

Primary Outcome Measures

Name	Time	Method
subtypes of monocytes	1 day	evaluate different subtypes of monocytes in brain-death donors by collecting portal and peripheral blood after lapaotomy and before dissection
evaluate effect of intestinal manipulation	1 day	evaluate the effect of intestinal manipulation on the different subtypes of monocytes and pro-/anti-inflammatory cytokines

Trial Locations

Locations (1)

University Hospitals Leuven; 🇧🇪 Leuven, Vlaams-Brabant, Belgium