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Impact of medicines on red blood cells

Not Applicable
Conditions
Health Condition 1: D590- Drug-induced autoimmune hemolyticanemia
Registration Number
CTRI/2024/04/065162
Lead Sponsor
Kasturba Medical College Manipal
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Including all patients who are getting admitted under department of Infectious Diseases, who are on antimicrobials

Exclusion Criteria

Excluding patients with known cases of

1. Inherited hemolytic anemia like sickle cell anemia, thalassemia, hereditary spherocytosis etc

2. Autoimmune diseases like rheumatoid arthritis, lupus, multiple sclerosis etc

3. Cases of poisoning like Arsenic, Copper

4. Non hemolytic anemia like iron deficiency anemia, anemia due to chronic disease, chronic kidney disease, bone marrow dysfunction

5. All other causes of hemolysis

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Frequency of antibodies produced to red cell antigen in patients on antimicrobials can be determined. <br/ ><br>This will allow for a close monitoring of the patient before the occurrence of serious hemolysis. <br/ ><br>It will also help the treating doctor to decide on how frequently a patient should be monitored for clinical evidence of hemolysisTimepoint: Baseline and day 7
Secondary Outcome Measures
NameTimeMethod
ILTimepoint: NI
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