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Efficacy of Naso-Esophageal Tube Feeding in Patients With High Cervical Spinal Cord Injury.

Not Applicable
Not yet recruiting
Conditions
Spinal Cord Injury Cervical
Interventions
Device: Naso-Esophageal Tube Feeding
Device: Nasogastric Tube Feeding
Behavioral: Routine treatment
Registration Number
NCT06393205
Lead Sponsor
Copka Sonpashan
Brief Summary

The goal of this clinical trial is to compare the differences in Pneumonia situation and nutritional status between Patients With High Cervical Spinal Cord Injury using Naso-Esophageal Tube Feeding and Nasogastric Tube. Patients will be randomly divided into an observation group and a control group, all receiving routine rehabilitation treatment. On this basis, the observation group will use Naso-Esophageal Tube Feeding for enteral nutrition support, while the control group will use Nasogastric Tube. Researchers will compare changes in Pneumonia situation and nutritional status of two groups of patients before and after the study to see if Naso-Esophageal Tube Feeding can improve the Pneumonia situation and nutritional status between Patients With High Cervical Spinal Cord Injury

Detailed Description

Naso-esophageal tube feeding is a medical procedure utilized to provide nutrition directly into the esophagus via a tube inserted through the nose. This method is employed when individuals cannot consume food orally due to various medical conditions, such as dysphagia (difficulty swallowing), neurological disorders, or conditions affecting the upper gastrointestinal tract.

The goal of this clinical trial is to compare the differences in Pneumonia situation and nutritional status between Patients With High Cervical Spinal Cord Injury using Naso-Esophageal Tube Feeding and Nasogastric Tube. Patients will be randomly divided into an observation group and a control group, all receiving routine rehabilitation treatment. On this basis, the observation group will use Naso-Esophageal Tube Feeding for enteral nutrition support, while the control group will use Nasogastric Tube. Researchers will compare changes in Pneumonia situation and nutritional status of two groups of patients before and after the study to see if Naso-Esophageal Tube Feeding can improve the Pneumonia situation and nutritional status between Patients With High Cervical Spinal Cord Injury

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria
  • High Cervical Spinal Cord Injury.
  • any degree of dysphagia at admission;
  • steady vital signs, without severe cognitive impairment or sensory aphasia, able to cooperate with the assessment.
Exclusion Criteria
  • damaged mucosa or incomplete structure in nasopharynx;
  • unfeasible to the support of parenteral nutrition;
  • simultaneously suffering from liver, kidney failure, tumors, or hematological diseases.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
the Naso-Esophageal Tube Feeding groupNaso-Esophageal Tube FeedingThe patients will be given Naso-Esophageal Tube Feeding and routine treatment, for 15 days.
the Naso-Esophageal Tube Feeding groupRoutine treatmentThe patients will be given Naso-Esophageal Tube Feeding and routine treatment, for 15 days.
The Nasogastric Tube Feeding groupNasogastric Tube FeedingThe patients will be given Nasogastric Tube Feeding and routine treatment, for 15 days.
The Nasogastric Tube Feeding groupRoutine treatmentThe patients will be given Nasogastric Tube Feeding and routine treatment, for 15 days.
Primary Outcome Measures
NameTimeMethod
Nutritional status-prealbuminDay 1 and day 15

The relevant indicators include prealbumin (PA, mg/L) from the blood test within 24h after admission and the last day of treatment, generally, with empty-stomach ones and in the morning.

Nutritional status-total proteinDay 1 and day 15

The relevant indicators include total protein (TP, g/L) from the blood test within 24h after admission and the last day of treatment, generally, with empty-stomach ones and in the morning.

Nutritional status-albuminDay 1 and day 15

The relevant indicators include albumin (ALB, g/L)from the blood test within 24h after admission and the last day of treatment, generally, with empty-stomach ones and in the morning.

Nutritional status-hemoglobinDay 1 and day 15

The relevant indicators include hemoglobin (Hb, g/L)from the blood test within 24h after admission and the last day of treatment, generally, with empty-stomach ones and in the morning.

Secondary Outcome Measures
NameTimeMethod
Body weightDay 1 and day 15

Body weight measurement of the infants was conducted by the same nurse according to the relevant standards.

Swallowing Quality of Life questionnaireDay 1 and day 15

Swallowing Quality of Life questionnaire was used to evaluate the quality of life, which consists of 44 items and divided into 11 main domains, including: overall satisfaction, understanding, diet, hydration, communication, respiratory issues, postoperative recovery, social impact, mental health, saliva control, and appearance. The maximum rough score was 220 points, which was converted into a standard percentage system in our study. As the scores increased, the quality of life was better.

Dysphagia Handicap IndexDay 1 and day 15

Dysphagia Handicap Index is a self-reported questionnaire used to assess the impact of dysphagia on an individual's quality of life. It typically consists of multiple questions related to the physical, functional, and emotional aspects of swallowing difficulties. The total score range varies between 0 and 100. A higher score indicates a greater perceived impact of dysphagia on the individual's quality of life.

PneumoniaDay 1 and day 15

The occurrence of pneumonia in patients was assessed before and after treatment. Specifically, first of all, the symptom assessment and physical examination were conducted to all patients, during which, the doctor would inquire symptoms related to pneumonia, such as cough, sputum production, difficulty breathing, chest pain, etc. and observe the patient's respiratory condition, including respiratory rate, breath sounds, and any abnormal signs in the chest.

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