ow-dose radiation therapy in treating patients with follicular non-Hodgkin's lymphoma

Phase 3

Completed

• Conditions: on-Hodgkin's follicular lymphoma; Cancer; Lymphoma

• Registration Number: ISRCTN65687030
• Lead Sponsor: niversity College London (UK)

Brief Summary

2014 results in http://www.ncbi.nlm.nih.gov/pubmed/24572077 2021 5-year follow-up results in https://pubmed.ncbi.nlm.nih.gov/33539729/ (added 05/02/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-12-01
• Study Completion: 2011-09-30
• Last Update Posted: 16 February 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 548

Inclusion Criteria

The study population will consist of either male or females over the age of 18 years who are diagnosed with histologically proven follicular lymphoma, for whom palliative radiotherapy has been indicated by virture of tumour bulk or anatomical position.

Exclusion Criteria

1. Stage 1A disease to be treated radically with radiotherapy
2. Histological sub-types other than follicular non-Hodgkin's lymphoma
3. Predicted prognosis less than 3 months
4. Chemotherapy within 4 weeks of planned radiotherapy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ocal progression-free interval

Secondary Outcome Measures

Name	Time	Method
<br> 1. Acute toxicity<br> 2. Late toxicity<br> 3. Tumour response<br> 4. Overall survival<br> 5. Health economic assessment<br>