Respiratory mechanics and ventilation using controlled exspiration (FLEX) in obese patients having elective surgery under general anesthesia
Not Applicable
- Conditions
- perioperative mechanical ventilation
- Registration Number
- DRKS00011182
- Lead Sponsor
- niversitätsklinikum Freiburg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
elective surgery, controlled ventilation, Obesity (BMI>30kg/m2)
Exclusion Criteria
known lung diseases, Pacemaker, implantable cardioverter/defibrillator, intracardial malformation
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method non-linear intratidal Compliance calculated with the generated respiratory data using the gliding-SLICE method. Respiratory data are collected during the entire experiment, calculation of compliance is performed after terminating the experiment.<br>(see also: Schumann et al. Estimating intratidal nonlinearity of respiratory system mechanics: a model study using the enhanced gliding-SLICE Method Physiol Meas 2009 Dec; 30:1341-1356; <br>Schumann et al. Analysis of dynamic intratidal compliance in a lung collapse model. Anesthesiology 2011 May;114(5):1111-1117)
- Secondary Outcome Measures
Name Time Method Oxygenation (SaO2, PaO2) determined by arterial blood gas samples; <br>point in time: after calibration (t0),after 10 minutes (t1) and after 20 minutes (t2)