A randomized, double-blind placebo-controlled trial for Zishen Yutai Pill for endometrial repair in patients after artificial abortio
- Conditions
- Endometrial injury after artificial abortion
- Registration Number
- ITMCTR2000003334
- Lead Sponsor
- Centre for Reproductive Medicine, Tongji Medical College, Huazhong University of Science and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Female
- Target Recruitment
- Not specified
1. Patients aged 18 to 40 years;
2. The patients who were diagnosed as early intrauterine pregnancy and asked for termination of pregnancy and accepted abortion;
3. The number of previous abortion 1-3;
4. Menstrual cycle in the first three months of pregnancy, 25-35 days and 3-10 days;
5. Objects who have been healthy without contraindications;
6. Patients who voluntarily cooperate with observation and treatment and have signed informed consent.
1. Patients who used proprietary Chinese medicine and hormone within the past month;
2. Subjects with previous allergic history to the test drug;
3. Patients with poor general conditions and intolerable to surgery;
4. Patients with previous endocrine abnormalities, uterine organic lesions and reproductive system tumors;
5. Patients with genital malformation, tumor or acute genital inflammation (such as acute pelvic inflammation, acute vaginitis, etc.);
6. The disabled patients (blind, deaf, dumb, mental disorder, mental disorder, physical disability) and the mentally ill patients specified by law;
7. Patients whose body temperature was above 37.5 degree C twice before operation;
8. Patients who have had the previous uterine cleaning for more than 4 times;
9. Patients with severe hepatorenal insufficiency.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endometrial thickness (mm);
- Secondary Outcome Measures
Name Time Method Menstruating time (day);Serum estradiol levels;Endometrial morphology;Uterine spiral artery resistance index;Serum progesterone levels;Duration of menstruation (days);Menstrual cycle time (days);