Associations Between Depression and Cardiovascular Disease - a Study of Patients With Late Onset Depression

Completed

• Conditions: Depression; Cardiovascular Disease; Coronary Artery Disease; Major Depressive Disorder

• Registration Number: NCT00818506
• Lead Sponsor: University of Aarhus

Brief Summary

Studies show that depression is a risk factor for the development of coronary artery disease (CAD). Furthermore there is an increased occurrence of depression in patients with CAD. Among other mechanisms atherosclerosis is believed to play a central role regarding these notable associations between depression and CAD. Moreover, patients with late onset major depression have an increased number of small lesions found in the white matter of the brain, the so-called white matter lesions. The main goal of this project is to examine if CAD is associated with depression and/or white matter lesions. CAD is evaluated using coronary CT angiography. Depression is evaluated using a semi-structured diagnostic interview. White matter lesions are quantified using cerebral magnetic resonance.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2009-01-06
• Study First Submitted QC: 2009-01-06
• Study First Posted: 2009-01-07
• Study Start: 2009-03
• Study Completion: 2012-06
• Status Verified: 2012-11
• Last Update Submitted: 2012-11-20
• Last Update Posted: 2012-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 55

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Center of Psychiatric Research, Aarhus University Hospital; 🇩🇰 Aarhus, Denmark