Effect Of Pippalyadi Churna in Female Infertility.

Phase 2/3

Not yet recruiting

Conditions: Diseases of the genitourinary system. Ayurveda Condition: VANDHYA,

Registration Number: CTRI/2025/04/085466

Lead Sponsor: Shafaq Zahra Ansari

Brief Summary: Anovulation or inability to produce a fertile ovum is an important reason among woman facing infertility and still it is a growing problem due to changing life style, faulty food habits, environment, stress provoking jobs. In such patients ovulation induction is a rescuer. Over the past few decades modern medical field developed modalities like Clomid Therapy, Letrozole, Insulin sensitizing drugs, Ovarian drilling, HCG injections, Gonadotropin therapy but all these modalities are associated with many complications like Ovarian Hyperstimulation Syndrome (OHSS), Multiple Pregnancy etc. Considering all these drawbacks an appropriate management of anovulation is required. In Ayurveda, Anovulation is quoted as the result of vitiation of doshas in reproductive system of a woman suffering from menstrual disorders. Vata dosha is controller of any type of movement in the body and regeneration and growth are facilitated by Kapha. Lower part of the body is seat of Vata. When Vata is vitiated by its aggravating factors or vitiated due to the occlusion or obstruction by Kapha it cannot govern its normal functions and anovulation state persists. Among the three doshas, Vata plays major role in physiology and pathology of reproductive tract and the drug which is fruitful in Agnimandhya i.e deepana & pachana may also be useful for anovulation. Anovulation is mainly related to Rasavaha and Artavaha strotas, according to Samprapti of Nastabeej there is a sanga type of strotodusti due to dosha dushya sammurchhana. Pippalayadi Churna has mainly ushna virya which remove strotorodha and increase the secretion of endometrial glands by opening the vessels, Keeping this hypothesis in mind it is planned to evaluate the effect of Pippalyadi Churna in Anovulatory factor of infertility.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: Female

Target Recruitment: 60

Inclusion Criteria

1 Diagnosed married female patients fulfilling criteria of Stree Vandhyatva of age group 18 to 35 years.
2 Patients having regular mensturation.
3 Patients having complaints of failure to conceive due to Anovulatory cycle.
4 Primary and secondary type of infertile patient will be taken for study.

Exclusion Criteria

1 Patients having physiological anovulatory conditions like pregnancy lactation and menopause.
2 Patients suffering from known chronic illness, cardiac disease and known case of thyroidism.
3 Patients having Abnormal Uterine Bleeding, cervical tumor, polyp cancer of cervix, uterine fibroid.
4 Known case of congenital anomalies of female genital organ like infantile uterus and absence of ovaries.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To Study Effect Of Pipplyadi Churna in Stree Vandhyatva with special refference to Anovulatory Cycle	14 days from Day 5th to Day 18th of Menses for 2 consecutive cycles

Secondary Outcome Measures

Name	Time	Method
1. To study Stree Vandhyatva according to Ayurveda.	2. To study female Infertility with special reference to Anovulation in detail

Trial Locations

Locations (1): LRP Ayurvedic Medical college Hospital Post Graduate Institute and Research Center Islampur
🇮🇳
Sangli, MAHARASHTRA, India
LRP Ayurvedic Medical college Hospital Post Graduate Institute and Research Center Islampur
🇮🇳Sangli, MAHARASHTRA, India
Dr Shafaq Zahra Ansari
Principal investigator
09579842780
shafaqzahra0808@gmail.com