study of Dhatryadi Kwatha and Shatavaryadi Kwatha in cystitis

Phase 2

Not yet recruiting

• Conditions: Acute cystitis. Ayurveda Condition: mootrakrichchhra,

• Registration Number: CTRI/2021/11/038259
• Lead Sponsor: Dr Arjun Sable

Brief Summary

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|The Title of this Study is - **An openlabelled,  randomised, comparativeclinical study to evaluate the efficacy of *Dhatryadi* *Kwatha* and *Shatavaryadi**Kwatha* in *Pittaj* *Mootrakrichchhra*.**

This study is planned to assess the efficacy of *Dhatryadi Kwatha* on *Pittaj Mootrakrichchhra* and to provide better option for its management. In developing country, disease has more prevalence due to poor personal hygiene, mal nutrition, and environmental condition. *Pittaj* *Mootrakrichchhra* is a disease where *Ayurveda* offer a better hand than any other medical system.Scope of present work is limited up to *Pittaj* *Mootrakrichchhra* only. Recurrence of disease is very common. There are eight types of *Mootrakrichchhra* of which *Pittaj* *Mootrakrichchhra* have symptoms like burning micturation, frequent micturation. According to the symptoms of Urinary Tract Infection (U.T.I.) and *Pittaj Mootrakrichchhra*, we can compare the both in modern science.  Hence, this subject is considering for study, to assess the efficacy of *Dhatryadi Kwatha in* *Pittaj Mootrakruchchhra.*In routine practice there are many patients presenting with *Mootrakrichchhra* and hence to treat this many trials have been done.  Many *Ayurvedic* preparation trials have been done for *Pittaj* *Mootrakrichchhra* Study. For study *Dhatri, Draksha, Vidarikand, Yashtimadhu, and Gokshur Yoga* will be used in the form of *Kwatha* for convenience and palatability. This is an attempt to study the efficacy of  *Dhatryadi Kwatha* and *Shatavaryadi Kwatha in Pittaj* *Mootrakrichchhra* in same dose, *kala* and duration. The contents of *Dhatryadi Kwatha* i.e. *Dhatri*, *Draksha*, *Vidarikand*, *Yashtimadhu*, and *Gokshur* are easily available and are cheap. Properties mentioned in text are useful for *Pittaj Mootrakrichchhra*. This study will be clinical evidence for *Pittaj Mootrakrichchhra.*In *Ayurveda*, *Mootrakrichchhra* treatment has many formulations which are claimed to be effective in relieving the symptoms, as *Ayurvedic* drugs taken in proper dosage & continued treatment gives best result with minimal or no side effects.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2021-11-24
• Study Start: 2021-11-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• 1.Patients will be selected from age group of 18 to 60 years irrespective of gender, religion, socio-economic status, marital status with informed written consent.
• 2.Patients presenting with cardinal symptoms of Pittaj Mootrakrichchhra mentioned in Charak Samhita, Chikitsasthan 26 such as 1.Sapeeta mutrapravrutti 2.Sarakta mutrapravrutti 3.Muhurmuh umutrapravrutti 4.Sadaha Mutrapravrutti 5.Sashul Mutrapravrutti Patient having above 2 or more complaints along with sadah mutrapravrutti.

Exclusion Criteria

• Diagnosed patient of 1.Uncontrolled Diabetes Mellitus and Known case of Diabetes Mellitus, Tuberculosis 2.Renal failure.
• 3.Patient of chronic cystitis with bladder wall change.
• 4.Benign or malignant tumors of bladder 5.Pregnant women.
• Known case of Mutraghat, Ashmari (renal, vesicular calculus), Benign Prostate Hypertrophy, Urethral stricture, Phymosis, Tumours, Trauma to urogenital tract.
• Congenital causes and Obstructive pathology.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.To assess the efficacy of ‘Dhatryadi Kwatha’ in ‘Pittaj Mootrakrichchhra’ by clinical parameter.	5 days
Sapeeta mutrapravrutti,	5 days
Sashul Mutrapravritti	5 days
Sarakta mutrapravrutti, Muhurmuhu mutrapravrutti, Sadaha Mutrapravritti,	5 days
2.To assess the efficacy of ‘Dhatryadi Kwatha’ in ‘Pittaj Mootrakrichchhra’ by Routine examination of urine.	5 days

Secondary Outcome Measures

Name	Time	Method
1.To develop evidence based research for efficacy of ‘Dhatryadi kwatha’ in ‘Pittaj Mootrakrichchhra’.	2.To generate data of good standardized drug of herbal origin with good efficacy and less side effects. To study the changes in pH of urine with Dhatryadi kwatha

Trial Locations

Locations (1)

Sane Guruji Aarogya Kendra; 🇮🇳 Pune, MAHARASHTRA, India

Sane Guruji Aarogya Kendra

🇮🇳Pune, MAHARASHTRA, India

Dr Arjun Annasaheb Sable

Principal investigator

8482947594

asable251194@gmail.com