Heart scanning in patients with longstanding kidney injury and hypertension

Completed

• Conditions: Routine evaluation of healthy individuals; Hypertensive chronic kidney disease with stage 1 through stage 4 chronic kidney disease, or unspecified chronic kidney disease,

• Registration Number: CTRI/2022/10/046628
• Lead Sponsor: Department of Cardiology

Brief Summary

This study is mainly done to detect subclinical myocardial deformation in CKD, and hypertensive patients in comparison with healthy individuals.

Primary objectives:

To compare left atrial strain and left ventricular torsion between chronic kidney disease and hypertensive patients in comparison with healthy controls

Secondary objectives:

·       To compare myocardial deformation imaging parameters between CKD and HTN patients with and without left ventricular hypertrophy.

·    To compare diastolic function by transmitral pulsed wave doppler, mitral annular tissue Doppler and Pulmonary venous Doppler flow patterns between CKD patients, hypertensive patients and healthy controls.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-11-15
• Last Update Posted: 2023-04-07
• Study Completion: 2023-04-14

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 141

Inclusion Criteria

• Inclusion criteria : Cases: 1.Patients ( aged ≥ 18 years) with 3rd ,4th and 5th stages of chronic kidney disease.
• 2.Hypertensive patients who undergone Echocardiography showing with or without Left ventricular hypertrophy (LVH).
• Controls: Healthy controls who come for routine cardiac evaluation are referred for echocardiography.

Exclusion Criteria

1.Arrhythmias 2.Valvular Heart Disease 3.Coronary Artery Disease 4.Congenital Heart Disease 5.Patients with poor echo window 6.Past history of stroke.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare left atrial strain and left ventricular torsion between chronic kidney disease and hypertensive patients in comparison with healthy controls.	1 year

Secondary Outcome Measures

Name	Time	Method
To assess the ventricular systolic and diastolic function and other demographic features in CKD, hypertensive and healthy individuals.	1 year

Trial Locations

Locations (1)

Kasturba Hospital; 🇮🇳 Udupi, KARNATAKA, India

Kasturba Hospital

🇮🇳Udupi, KARNATAKA, India

Sameeksha S Shetty

Principal investigator

9632285017

shettysameeksha156@gmail.com