Novel Equation for Estimating Resting Energy Expenditure

Completed

• Conditions: Resting Energy Expenditure; Chronic Kidney Disease

• Registration Number: NCT03377413
• Lead Sponsor: Peking University First Hospital

Brief Summary

The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations are not applicable to CKD patients,so we aim to develop and validate a equation for estimating resting energy expenditure in CKD patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-12-14
• Study First Submitted: 2017-12-14
• Study First Submitted QC: 2017-12-14
• Study First Posted: 2017-12-19
• Primary Completion: 2020-01-31
• Study Completion: 2020-02-01
• Status Verified: 2020-10
• Last Update Submitted: 2020-10-13
• Last Update Posted: 2020-10-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• CKD 3-5 stages
• Age:18-80 years old

Exclusion Criteria

• Dialysis and kidney transplantation;
• Acute complications to hospitalization
• 1 month prior to the study;
• Acute or chronic infections, cancer and other wasting diseases in the past year;
• Thyroid dysfunction;
• Acute onset of podagra; Musculoskeletal diseases;
• Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD);
• History of hormonal drugs use;
• During pregnancy or lactation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Novel equation development	September 1, 2017 to June 1, 2018	Developed equation for estimating REE in CKD 3-5 stages patients
Novel equation validation	June 1, 2018 to March 1, 2019	Validate the noval equation with REE obtained by indirect calorimetry (IC).

Trial Locations

Locations (1)

Renal Division and Institute of Nephrology, Peking University First Hospital; 🇨🇳 Beijing, Beijing, China