Presence of Microplastics and Nanoplastics in Neurosurgery Patients
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- microplastics
研究概览
简要总结
Plastic particles are a ubiquitous pollutant in the living environment and food chain, so far, plenty of studies have reported the internal exposure of microplastics and nanoplastics in human tissues and enclosed body fluids.
Neurosurgery is the only department that can open the skull. In addition to blood and cerebrospinal fluid, there are brain tissue and tumors in the presence of lesions. Whether any of these microplastics and nanoplastics are present remains a mystery. This prospective observational study will harvest biological samples of neurosurgery patients.
The objective of this research is to be able to detect microplastics and nanoplastics on blood and operation samples of neurosurgery patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-80 years
- •Any type of neurosurgery
排除标准
- •·refusal of the patient to participate
结局指标
主要结局
microplastics
时间窗: baseline, intraoperative
Detection of microplastics in human brain tissue and the blood undergoing neurosurgery
nanoplastics
时间窗: baseline, intraoperative
Detection of nanoplastics in human brain tissue and the blood undergoing neurosurgery
次要结局
未报告次要终点
研究者
Xiaolin Chen, MD
Director
Beijing Tiantan Hospital