The Effects of Demographic and Clinical Data of Patients on the Assessment of Cerebral Oxygen Monitoring Values Applied During Coronary Artery Bypass Grafting
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Regional oxygen saturation values
研究概览
简要总结
The aim of this study is to examine the effects of patients' clinical and demographic datas on cerebral oxygen saturation values. Brain oxygenation is measured using near infrared spectroscopy (NIRS). The primary outcome measure of the study is the regional oxygen saturation (rSO2) values measured on the monitor at twelve time points. The other primary outcome measures consist of baseline arterial and venous blood gas analysis and baseline activated clotting time measurements.
详细描述
This prospective observational study analyzes 80 patients between the ages of 25-80 years who are undergoing elective coronary artery bypass grafting (CABG) surgery. Demographic data of the patients such as age, gender, comorbidities, body mass index are recorded. In addition to standard monitoring, cerebral oximetry monitoring (NIRS) is applied to the patients. Baseline arterial and venous blood gas analysis values, baseline activated clotting time measurements are recorded. Durations of anesthesia, surgery , cardiopulmonary bypass , aortic cross- clamping are recorded. Time points for rSO2 values are baseline, induction, sternotomy, cannulation, pump entry, cross clamp placement, 34º C ,36º C, lowest temperature, cross clamp removal, pump exit, skin closure.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Accepting to participate in the study
- •Undergoing elective coronary artery bypass grafting surgery
- •Age 25-80 years Ejection fraction 30% and above
排除标准
- •Non volunteers
- •Age <25 or >80 years
- •Ejection fraction below 30%
- •Patients with history of neurological disease or neurosurgery
- •Emergency surgery
- •Concurrent valve surgery
- •Patients with history of carotid artery stenosis
- •Patients with need for preoperative intraaortic balloon pump or inotropic support
结局指标
主要结局
Regional oxygen saturation values
时间窗: Baseline and peroperative measurements until the and of surgery
Regional oxygen saturation values measurement at twelve points.
Baseline arterial blood gas analysis
时间窗: Within 5 minutes after arterial cannulation for the baseline measurement
The baseline arterial blood gas sample taken from the patient after arterial cannulation
Venous blood gas analysis
时间窗: Within 5 minutes after central jugular venous cannulation
Venous blood gas sample taken from the patient after central jugular venous cannulation
Baseline activated clotting time measurement
时间窗: Within 5 minutes after arterial cannulation for the baseline measurement
The baseline measurement of activated clotting time after arterial cannulation
次要结局
未报告次要终点
研究者
Tuna Şahin
Anesthesiologist
Adana City Training and Research Hospital