Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation (DOHECOV)

Recruiting

• Conditions: Congestion, Venous

• Registration Number: NCT06914336
• Lead Sponsor: University Hospital, Brest

Brief Summary

The purpose of the study is to investigate venous congestion using hepatic vein doppler for ICU patients with invasive mechanical ventilastion. The primary outcome is the systolic to diastolic hepatic vein velocity ratio S/D . The objective is to find a significant association between S/D and different congestion indicators.

Detailed Description

Not available

Study Timeline

• Status Verified: 2025-03
• Study Start: 2025-03-24
• Study First Submitted: 2025-03-24
• Study First Submitted QC: 2025-04-04
• Last Update Submitted: 2025-04-04
• Study First Posted: 2025-04-06
• Last Update Posted: 2025-04-06
• Primary Completion: 2028-10-31
• Study Completion: 2028-10-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• intubated for more than 24 hours

Exclusion Criteria

• Chronic end-stage renal disease on admission
• Atrial Fibrillation
• Cirrhosis
• Portal thrombosis
• Refusal to participate
• non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity
• Under legal protection.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Systolic to diastolic hepatic vein velocity ratio S/D	24 hours after intubation and after every 48 hours until extubation up to 12 weeks	Relate S/D ratio to clinical data on venous congestion: input/output balance, weight variation, renal insufficiency, diuresis, edema.

Trial Locations

Locations (1)

Chu Brest; 🇫🇷 Brest, France