Prognostics in the Treatment Evaluation of the National System for Veterans' Care
Recruiting
- Conditions
- psychische stoornissen: Trauma- en stressorgerelateerde stoornissen, posttraumatische stress stoornisposttraumatic stress disorder10002861
- Registration Number
- NL-OMON49653
- Lead Sponsor
- Stichting Centrum 45 (Oegstgeest)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 22
Inclusion Criteria
Soldiers and veterans who participated in a military deployment and meet
diagnostic DSM-5 criteria for PTSD or subthreshold PTSD. Further inclusion
criteria are age between 18 and 65 years and indicated to receive
trauma-focused psychotherapy.
Exclusion Criteria
A potential subject who meets any of the following criteria will be excluded
from participation in this study: acute suicidality and severe psychiatric
co-morbidity. For the subjects that will undergo the dexamethason supression
test more exclusion criteria are: allergy to one of the ingredients of
dexamethasone and (intended) pregnancy or breastfeeding.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary outcome measure is change during the first year of treatment in<br /><br>PTSD symptom severity (between T1 and T3). We will develop a prognostic model<br /><br>that predicts treatment outcome based on PD (such as, stigma, shame, and<br /><br>guilt), NP (executive functions and verbal memory), and PP (the stress- and<br /><br>immune system) factors collected during the study. </p><br>
- Secondary Outcome Measures
Name Time Method <p>The secondary outcome measures are change during the first year of treatment in<br /><br>depressive symptoms severity and level of daily functioning (between T1 and<br /><br>T3). </p><br>