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A comparative study of the effect of intravenous administration of ketorolac and acetaminophen on pain relief after Uvulopalatopharyngoplasty surgery

Phase 3
Recruiting
Conditions
vulopalatopharyngoplasty.
Registration Number
IRCT20240402061399N1
Lead Sponsor
Yazd University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

patient with american society of anesthesiologists physical status classification(ASA)
BMI?35

Exclusion Criteria

heart disease
uncontrolled hypertension
uncontrolled diabetes
gastrointestinal disease, Gastroesophageal reflux disease (GERD)
Patient non-cooperation
anti coagulant usage
drug abuse
corticosteroid usage
renal disease
surgery time more than 2 hr

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pain intensity, need for narcotics, time to start swallowing liquids, time to start swallowing solids. Timepoint: Number of times the need for narcotics during the first 48 hours after surgery, time to start swallowing liquids and solids, pain intensity 6, 12, 24 and 48 hours after surgery. Method of measurement: Pain intensity based on Visual Analogue Scalescale, number of times the need for narcotics, time to start swallowing liquids and solids.
Secondary Outcome Measures
NameTimeMethod
Heart rate, blood pressure, slow bleeding, nausea, vomiting, rash, dizziness. Timepoint: Heart rate and blood pressure before and after induction of anesthesia, after extubation, 0, 15 and 60 minutes into recovery. Bleeding in the first 48 hours after surgery. Nausea, vomiting, rash and dizziness in the first 24 hours after surgery. Method of measurement: Heart rate per minute, blood pressure mm Hg. Bleeding, nausea and vomiting, rash and dizziness or not.
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