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Validation of the O3 Regional Somatic Tissue Oxygenation Monitor

Not Applicable
Completed
Conditions
Oxygen Deficiency
Registration Number
NCT04584788
Lead Sponsor
Masimo Corporation
Brief Summary

Testing the absolute accuracy of the Masimo O3 regional oximeter in reading somatic tissue oxygenation in healthy volunteers under controlled hypoxia.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
37
Inclusion Criteria
  • Age between 18 and 45 years, inclusive
  • Willing and able to provide written informed consent
  • Healthy subjects
Exclusion Criteria
  • Pregnant women
  • Presence of any cardiovascular or pulmonary disease
  • Exposure to high altitude(s) (>2000 m) within 30 days prior to the study
  • Known allergy to intravenous contrast medium or heparin
  • Subject has skin abnormalities affecting the digits such as psoriasis, eczema, angioma, scar tissue, burn, fungal infection, substantial skin breakdown, nail polish or acrylic nails that would prevent monitoring of SpO2 levels during the study
  • Patients deemed not suitable for the study at the discretion of the Investigator

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Accuracy of O3 Sensor by ARMS Calculation of Percent rSO21 visit up to 8 hours

Accuracy of the sensors will be determined by comparing somatic regional oxygen saturation (rSO2) readings from the O3 sensor and blood reference oxygen saturation values and calculating the Arithmetic root mean square (ARMS).

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Site 1

🇳🇱

Groningen, Netherlands

Site 1
🇳🇱Groningen, Netherlands

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