Modélisation de l'œil Myope Infantile Par IRM et OCT
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Eye anatomy
研究概览
简要总结
Myopia (nearsightedness) is increasing worldwide and is becoming a serious public health problem. Studies estimate that by 2050, if no action is taken, almost half of the world's population will be myopic. About 10% of people could develop severe myopia, which increases the risk of serious eye problems such as retinal detachment, damage to the macula, or glaucoma.
Children are particularly affected because myopia often worsens as they grow. Several treatments are now available to slow the progression of myopia in children, but these treatments are not equally effective for everyone. Some children respond better than others, and the reasons for these differences are not yet well understood. One possible explanation is that differences in eye anatomy may influence the effectiveness of a treatment. This suggests that myopia treatments may need to be tailored to each child. By studying the anatomy of the eye, researchers could improve and personalize myopia control strategies.
The study entitled "Eye imaging for the study of childhood myopia" aims to better understand the structure of children's eyes. The study will collect clinical data, including images of the eye taken with MRI and measurements of the eye obtained using standard eye examination devices. The data will then be analyzed using image-processing and statistical methods to allow a detailed study of children's eye anatomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 6 Years 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Spherical equivalent under cycloplegia greater -9.75 D and less than 2 D
- •Beneficiary of social security
- •Written consent from both holders of parental authority (or from one in case of exclusive parental authority)
排除标准
- •Declared neurological deficit, including history of epileptic pathology or sensory-motor coordination disorders, vestibular or cerebellar pathology (for example, balance disorders)
- •Current or progressive pathology of the eyes or their appendages that may affect vision, other than myopia (examples: glaucoma, retinitis pigmentosa…)
- •Declared aphakia or pseudophakia (intraocular implant)
- •Ocular motility problem such as strabismus or nystagmus
- •Contraindication to MRI (claustrophobia, implanted devices such as pacemaker, etc.)
- •Wearing fixed orthodontic appliances that affect the quality of orbital MRI scans
研究组 & 干预措施
MRI and ophthalmological measurements
All enrolled participants will undergo the same eye examinations such as head MRI and ophthalmological measurements
干预措施: Ophtalmic measurements to estimate geometrical distances (Device)
MRI and ophthalmological measurements
All enrolled participants will undergo the same eye examinations such as head MRI and ophthalmological measurements
干预措施: MRI (Device)
MRI and ophthalmological measurements
All enrolled participants will undergo the same eye examinations such as head MRI and ophthalmological measurements
干预措施: Ophtalmic measurements to measure wavefront aberrations (Device)
结局指标
主要结局
Eye anatomy
时间窗: From enrollment to 3 months after enrollment
This set of data will enable an in-depth study of the eye anatomy: MRI will provide anatomical characteristics of the eyeball and its surrounding tissues such as the optical nerve. Ophtalmic measurements will provide anatomical characteristics of the eye's refractive system, such as corneal pachymetry, with optimal geometric resolution. Thus, MRI images and ophtalmic measurements will be combined to study the overall eye anatomy. Period: From inclusion up to 3 months after inclusion
次要结局
未报告次要终点