Hypocalcemia as a marker of disease severity in children with dengue
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 42
- 试验地点
- 1
- 主要终点
- Proportion of patients with hypocalcemia among those classified with severe dengue versus non-severe dengue.
研究概览
简要总结
This observational study, conducted at GTB Hospital from August 2025 to November 2026, investigates whether low serum calcium levels (hypocalcemia) can serve as a predictor of disease severity in pediatric dengue patients aged 6 months to 12 years. The study aims to correlate calcium levels with clinical severity, platelet count, hematocrit, and complications. By identifying hypocalcemia early, the research hopes to improve monitoring and outcomes in children with dengue. A total of 42 severe dengue cases will be recruited, along with all non-severe cases.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 6.00 Month(s) 至 12.00 Year(s)（—）
- 性别
- All
入选标准
- •Probable dengue and confirmed dengue as per WHO guidelines of age 6 months to 12 years Admission within first 5 days of fever.
排除标准
- •Children with known metabolic or endocrine disorders of calcium metabolism Children with chronic renal or hepatic disease or malignancy Patients already receiving calcium or vitamin D supplements Patients on steroids or immunosuppressives.
结局指标
主要结局
Proportion of patients with hypocalcemia among those classified with severe dengue versus non-severe dengue.
时间窗: within 24 hours of admission
次要结局
- Correlation coefficients between calcium levels and(Platelet count and Hematocrit)
研究者
Dr Anjali Kumari
UNIVERSITY COLLEGE OF MEDICAL SCIENCES DELHI