Impact of Neuropsychological Disorders on Visual Exploration, Walking Initiation and Walking in Multiple Sclerosis
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 32
- Locations
- 3
- Primary Endpoint
- Cadence of walking (in cycles.min-1)
Study Overview
Brief Summary
The study involves MS patients with and without neuropsychological disorders.
The patient will benefit from:
- A routine neuropsychological assessment, including a cognitive and emotional assessment
- A clinical examination
- A three-dimensional analysis of movement
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Supportive Care
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 55 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Understanding and able to speak French
- •Carriers of MS with relapsing remitting form (RRMS-RR) with an EDSS <4
- •No significant motor, cerebellar or somesthesia disorders of the upper limbs or visual disturbances (side to a visual EDSS <2)
- •Absence of corticosteroid intake in the last four weeks
- •Benefiting from health insurance coverage
- •Not showing any flare-ups or worsening of the disease in the last 6 weeks
- •No botulinum toxin injection for more than 4 months
Exclusion Criteria
- •People with previous neurological pathologies, head trauma with loss of consciousness, psychiatric pathologies, serious general ailments, perceptual or dysarthric disorders preventing verbal communication or reading,
- •Treatment with psychotropic drugs (except benzodiazepines and hypnotics).
- •Refusal to participate after clear and fair information about the study.
- •Adults under tutorship, curatorship or safeguard of justice
- •With orthopedic treatment influencing walking
- •Pregnant woman
Arms & Interventions
patients without neuropsychological disorders
Intervention: Three dimensional gait analysis with eyetracking (Other)
patients with neuropsychological disorders
Intervention: Three dimensional gait analysis with eyetracking (Other)
Outcomes
Primary Outcomes
Cadence of walking (in cycles.min-1)
Time Frame: 60 days
The kinematics of the initiation of walking and walking will be appreciated thanks to the variables calculated at the level of the joints of the lower limbs as well as the spatio-temporal parameters without and with management of obstacles (taking a step, balloon)
Range of motion in the lower limbs in degrees
Time Frame: 60 days
The kinematics of the initiation of walking and walking will be appreciated thanks to the variables calculated at the level of the joints of the lower limbs as well as the spatio-temporal parameters without and with management of obstacles (taking a step, balloon)
Step length (in m)
Time Frame: 60 days
The kinematics of the initiation of walking and walking will be appreciated thanks to the variables calculated at the level of the joints of the lower limbs as well as the spatio-temporal parameters without and with management of obstacles (taking a step, balloon)
Walking speed (in m.s-1)
Time Frame: 60 days
The kinematics of the initiation of walking and walking will be appreciated thanks to the variables calculated at the level of the joints of the lower limbs as well as the spatio-temporal parameters without and with management of obstacles (taking a step, balloon)
Secondary Outcomes
- Ocular fixation time (measured in ms)(60 days)
- Displacements (in mm) during walking(60 days)
- Muscle contractions determined by the electromyogram (EMG) (mV)(60 days)
- Acceleration (in mm.s-2) during walking(60 days)
- Joint angles(60 days)