Incidence and clinical impact of serum HYperamylasemia (POH) after Pancreatectomy on Postoperative Outcome and patient safety
Recruiting
- Conditions
- All patients undergoing a pancreatic resection.
- Registration Number
- DRKS00031860
- Lead Sponsor
- niversitätsklinikum Carl Gustav Carus
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
All patients undergoing pancreatic resection for malignant and benign disease
with or without pancreatic anastomosis
- Patients aged 18-85 years
- Willingness to participate as demonstrated by giving a written informed consent.
Exclusion Criteria
- Necrosectomy (endoscopic or open) for primary acute pancreatitis or within laparotomy
- Age less than 18 years
- Surgical drainage procedures without pancreatic resection (cystojejunostomy for pancreatic pseudocysts)
- One-stage total pancreatectomy
- Missing written consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - To evaluate the incidence and assess the value of postoperative biochemical <br>changes for PPAP in short-term outcome (incidence and severity of <br>complications represented in the Clavien-Dindo Classification (CDC) and <br>Comprehensive Complication Index (CCI)). <br>- To confirm and complement the definition and classification of postoperative <br>acute pancreatitis (PPAP) of the international study group of pancreatic surgery <br>(ISGPS).
- Secondary Outcome Measures
Name Time Method - To evaluate postpancreatectomy biochemical changes (lipase, white blood cells (WBC), CRP) and their clinical significance for the postoperative course. <br>- To develop clinical scores for predicting severe postoperative complications after pancreatic resection. <br>- To provide knowledge for effective early management of complications to <br>reduce morbidity