Quality of Life Change in Patients Undergoing Parathyroidectomy With Secondary Hyperparathyroidism Due toEnd-stage Renal Failure: a Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 60
- 主要终点
- Quality of life scores change with respect to time
研究概览
简要总结
The purpose of this study is to characterize changes in quality of life in patients who had undergone parathyroidectomy for secondary hyperparathyroidism due to end-stage renal disease, based on data extracted from an established database
详细描述
Data were retrospectively collected from an established database of patients who underwent surgery for renal secondary hyperparathyroidism (SHPT). Extracted information included demographic and clinical characteristics (age, gender, education level, clinical symptoms), baseline quality of life assessed by the 36-item Short-Form Health Survey (SF-36), and completed follow-up assessments of SF-36 scores, depression, and anxiety at one, three, six months, and one year postoperatively.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥18 years； Patients who had undergone parathyroidectomy for secondary hyperparathyroidism due to end-stage renal disease.
排除标准
- •Patients who underwent kidney transplantation during the study period. Patients with postoperative whole blood parathyroid hormone levels >300 pg/mL within the first week after surgery.
- •Patients with missing postoperative quality of life assessment data.
结局指标
主要结局
Quality of life scores change with respect to time
时间窗: up to 1 year
Quality of life was assessed using the 36-item Short Form Health Survey (SF-36) scale. Completed responses for each of the 36 items were extracted from the database. Item responses were aggregated to calculate scores for each of the eight dimensions. Scores for each dimension range from 0 to 100, with higher scores indicating better health status
次要结局
- Anxiety and depression score change with respect to time(up to 1 year)
- Bone pain scores change with respect to time(up to 1 year)
- Length of hospital stay(an average of 1 week)
研究者
Chunling Jiang
Professor
West China Hospital