CTRI/2025/08/092831Not yet recruitingNot Applicable
InVivo Confocal microscopy on Infectious Scleritis
L V Prasad Eye Institute1 site in 1 country30 target enrollmentStarted: August 25, 2025Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- L V Prasad Eye Institute
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Able to diagnose infective organism in patients of infectious scleritis
Study Overview
Brief Summary
A topical anesthetic (Paracain) will be applied to ensure comfort. After explaining the procedure, subjects will be positioned at the chinrest and instructed to fixate on a light source. IVCM will then be used to image the sclera in all four quadrants in Both eyes, focusing on clinically affected areas. Images will be stored for subsequent analysis.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 90.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •1.All age groups with adequate cooperation 2.Clinically diagnosed cases of scleritis with suspected infectious aetiology.
Exclusion Criteria
- •1.Excessive ocular discharge 2.Severe conjunctival chemosis 3.Corneal perforation or extreme corneal and scleral thinning 4.Significant eyelid abnormality that interferes with imaging (e.g., severe entropion, ectropion, blepharospasm) 5.History of tarsorrhaphy (partial or complete), unless lid separation is possible and scleral area is accessible for imaging.
- •6.Known allergy to topical anaesthetic drops.
Outcomes
Primary Outcomes
Able to diagnose infective organism in patients of infectious scleritis
Time Frame: 1 week , 1 month
Secondary Outcomes
- Compare with microbiology(1 day and 1 month)
Investigators
DrBhupesh Bagga
L V Prasad Eye Institute
Study Sites (1)
Loading locations...
Similar Trials
Recruiting
Not Applicable
Standardized Implementation and Quality Assessment System for Confocal EnteroscopyConfocal EnteroscopyQuality Assessment SystemStandardized ImplementationNCT07363291Shanghai Jiao Tong University School of Medicine600
Not yet recruiting
Not Applicable
Clinical, Microbial and Tissue-based Characterization of Patients Treated for Severe Temporomandibular Joint PathologyNCT07350239Örebro University, Sweden20
Recruiting
Not Applicable
Reflectance Confocal Microscopy and Molecular Correlation in Atypical Melanocytic LesionsMelanocytic NeviMelanoma (Skin Cancer)Next Generation Sequencing (NGS)NCT07277920University of Modena and Reggio Emilia200
Recruiting
Not Applicable
Intrastromal Moxifloxacin as an Adjunctive Therapy in Recalcitrant Bacterial KeratitisCorneal UlcerBacterial KeratitisRecalcitrant Infectious KeratitisNCT07394257Minia University60
Completed
Not Applicable
Conformity of Conjunctival Hyperemia Assessment in Soft Contact Lens Wearers Using Image J Analysis and Efron Degree SystemSoft Contact LensesNCT07290829Indonesia University52