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The effect of nutritional supplementation with CURCUMIN on RANKL/OPG ratio in gingival crevicular fluid of chronic periodontitis patients

Phase 4
Conditions
Health Condition 1: null- PATIENTS DIAGNOSED WITH CHRONIC GENERALIZED PERIODONTITIS
Registration Number
CTRI/2017/11/010494
Lead Sponsor
DR SUSHMA REDDY BHAVANAM
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1)Patients suffering from chronic periodontitis.

2)Patients between age group 30-60 years.

3)Probing pocket depth >=5mm.

4)Clinical attachment loss >=3mm.

5)Number of remaining teeth >=20 excluding third molars.

6)Systemically healthy patients.

7)Patients with no history of allergy to drugs used or prescribed inthis study.

Exclusion Criteria

1)History of underlying systemic disease.

2)Pregnant and lactating females.

3)Patients who have undergone periodontal treatment within a period of 6 months.

4)Under antibiotic/NSAIDS treatment during past 6 months.

5)Patients with plaque index > 1 and who donâ??t follow oral hygiene instructions after phase I therapy.

6)Patients on steroid therapy and oral contraceptives.

7)History of tobacco chewing and current or former smoker.

8)Patients who did not accept terms and conditions of the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
reduction in rate of bone loss after intake of curcumin tabletsTimepoint: 0, 6 WEEKS
Secondary Outcome Measures
NameTimeMethod
reduction in all clinical parameters except cinical attachment levelTimepoint: 0 and 6th week
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