Clinical study of HIPEC combined with traditional Chinese medicine elemene in the treatment of advanced colorectal cancer

Shanghai municipal hospital of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•(1) Gender: male or non-pregnant or lactating female;
•(2) Age 18-80 years old;
•(3) ECOG score <= 1;
•(4) Histopathologically diagnosed as adenocarcinoma/mucinous adenocarcinoma;
•(5) For newly treated patients with unilateral colorectal cancer, the intraoperative tumor stage is cT4N0-2M1, and CRS resection is feasible;
•(6) Laboratory examination within 2 weeks before enrollment: neutrophil count >= 2.0 x 10^9/L, platelet count >= 100 x 10^9 /L, hemoglobin >= 90g/L, serum total bilirubin <= 1.5 x ULN, Alanine aminotransferase and aspartate aminotransferase<= 2.5 x ULN, blood creatinine <= 1.5 x ULN;
•(7) Sign the informed consent form voluntarily.

•(1) Combined with primary malignant tumors of other organs (now or within the past 5 years) (except for patients with skin basal cell carcinoma and cervical carcinoma in situ receiving radical treatment);
•(2) Severe abdominal cavity infection or extensive abdominal cavity adhesions form an unbreakable partition;
•(3) Transition to open surgery or emergency surgery due to perforation or obstruction;
•(4) Any M1 or R0 resection is not found during the operation;
•(5) Patients with chickenpox or shingles;
•(6) Severe cardiopulmonary, vascular disease, mental illness or drug abuse.

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