ACTRN12614000891628
Completed
Phase 2
Acute randomised, double blind, placebo controlled crossover dietary intervention trial. A dose response evaluation of resveratrol supplementation on cerebrovascular function, mood and cognitive performance in type 2 diabetes mellitus.
Dementia Collaborative Research Centre0 sites40 target enrollmentAugust 21, 2014
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Diabetes
- Sponsor
- Dementia Collaborative Research Centre
- Enrollment
- 40
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Non\-insulin\-dependent type 2 diabetes mellitus adults; non\-smoking; women must be postmenopausal; dementia\-free, Clinic SBP between 130\-160mmHg ; BMI less than 40kg/m2; computer literate; have measurable ultrasound signal on both sides of the head; unlikely to change medication/supplements during the intervention.
Exclusion Criteria
- •Suspected dementia (3MS score of less than 78/100 determined at screening); Smokers or currently on nicotine therapy; Neurological conditions; Kidney/liver disease; Insulin therapy ; Major depression as diagnosed by a health care professional; Visual problems including the inability to distinguish the colours of red, green, blue and yellow; Illiterate; Physical difficulty in both hands that will impede on motor performance of the hand/arm; Unable to obtain a measurable signal in the MCA; Unwilling to provide two blood samples at each visit; Unwilling to maintain pre\-enrolment physical activity levels and dietary habits for the duration of the trial.; Unwilling to fast for 4hr; Currently consuming resveratrol or other grape extract supplements.
Outcomes
Primary Outcomes
Not specified
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