Opioid requirement between intravenous nalbuphine and morphine for postoperative analgesia after cesarean section under spinal anesthesia
Phase 4
Completed
- Conditions
- Healthy term pregnant womanPostoperative painSpinal anesthesiaNalbuphine
- Registration Number
- TCTR20210903005
- Lead Sponsor
- /A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 160
Inclusion Criteria
Term pregnancy with
-Age more than18 years
-Patient ASA physical status I-III.
-Scheduled for elective cesarean section under spinal anesthesia
-Can operate a patient-controlled analgesia (PCA) device.
Exclusion Criteria
-Known hypersensitivity to researched drugs
-History of chronic pain
-History of drug addict use
-Patient refuse for spinal anesthesia
-Medical complications eg heart diseases, diabetes, hypertension, renal or hepatic disease, obesity >=100 kilograms
-Gynecological complications eg myoma uteri, ovarian tumors
-Obstetrical complications eg multiple gestation, pre-eclampsia, fetal distress, IUGR(intra-uterine growth retardation), placenta previa
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Postoperative morphine and nalbuphine consumption 24 hours milligram
- Secondary Outcome Measures
Name Time Method umerical rating scale 6, 12 , 24 hour point,Nausea and vomiting 6,12,24 hour 0-3 point,Pruritus score 6,12,24 hour 0-3 point,Respiratory depression 6 12 24 hour Sedation score 0-3